All about alagille syndrome  causes of alagille syndrome symptoms of alagille syndrome diagnosis of Alagille syndrome treatment for alagille syndrome Articles in liver diseases - cirrhosis of the liver hemochromatosis primary sclerosing cholangitis primary biliary cirrhosis alagille syndrome alpha1-antitrypsin deficiency Crigler-Najjar syndrome hepatitis fatty liver liver transplant Wilson's disease ascites cholestasis jaundice liver encephalopathy liver failure portal hypertension |
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What causes alagille syndrome?
Alagille syndrome is generally inherited from one parent and there is a 50 percent chance that each child will develop the syndrome. Each affected adult or child may have all or only a few of the features of the syndrome. Frequently, a parent or brother or sister of the affected child will share the facial appearance, heart murmur or butterfly vertebrae, but have a completely normal liver and bile ducts. Bile is produced in the liver and then travels through the many small bile ducts in the liver into one large bile duct, and eventually into the intestines. In patients with alagille syndrome, the lack of small bile ducts inside the liver slows down the flow of bile from the liver to the intestines. Bile is composed of bilirubin, bile salts, cholesterol and metals such as copper. Bile acids are necessary to absorb fat and certain vitamins. When the bile flow is decreased, each of its components builds up in the body, and the body is not able to properly absorb fat and vitamins. This causes a wide range of symptoms. |
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More information on alagille syndrome
What is alagille syndrome? - Alagille syndrome is an inherited disorder that mimics other forms of prolonged liver disease seen in infants and young children.
What causes alagille syndrome? - Alagille syndrome is generally inherited from one parent and there is a 50 percent chance that each child will develop the syndrome.
What're the symptoms of alagille syndrome? - Symptoms of alagille syndrome are jaundice, pale, loose stools, and poor growth within the first three months of life.
How is alagille syndrome diagnosed? - The diagnosis of Alagille syndrome usually depends upon finding several different components of the syndrome in an individual.
What's the treatment for alagille syndrome? - Treatment of Alagille syndrome is based on increasing the flow of bile from the liver, maintaining normal growth and development. |
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