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All about primary sclerosing cholangitis (PSC) causes of primary sclerosing cholangitis symptoms of primary sclerosing cholangitis diagnosis of primary sclerosing cholangitis treatment for primary sclerosing cholangitis Articles in liver diseases - cirrhosis of the liver hemochromatosis primary sclerosing cholangitis primary biliary cirrhosis alagille syndrome alpha1-antitrypsin deficiency Crigler-Najjar syndrome hepatitis fatty liver liver transplant Wilson's disease ascites cholestasis jaundice liver encephalopathy liver failure portal hypertension

How is primary sclerosing cholangitis diagnosed?

The diagnosis is by imaging of the bile duct, usually in the setting of endoscopic retrograde cholangiopancreatography (ERCP, endoscopy of the bile duct and pancreas). Another option is magnetic resonance cholangiopacreaticography (MRCP), where magnetic resonance imaging is used to visualise the biliary tract.

Other tests often done are a full blood count, liver enzymes, bilirubin levels (usually grossly elevated), renal function, electrolytes. Fecal fat determination is occasionally ordered when the symptoms of malabsorption are prominent.

 

More information on primary sclerosing cholangitis (PSC)

What is primary sclerosing cholangitis? - Primary sclerosing cholangitis (PSC) is an inflammatory disease of the bile duct, which leads to cholestasis (blockage of bile transport to the gut).
What causes primary sclerosing cholangitis? - The causes of primary sclerosing cholangitis are not known, but many researchers think it might be an autoimmune disease.
What are the symptoms of primary sclerosing cholangitis? - The main symptoms of primary sclerosing cholangitis are itching, fatigue, and jaundice, which causes yellowing of the eyes or skin.
How is primary sclerosing cholangitis diagnosed? - The diagnosis of primary sclerosing cholangitis is made by imaging of the bile duct, usually in the setting of endoscopic retrograde cholangiopancreatography.
What is the treatment for primary sclerosing cholangitis? - Treatment for primary sclerosing cholangitis is directed at managing symptoms and opening narrowed bile ducts. 
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